I don't know if it will apply to a managed server – it will depend on the PHP-FPM configuration – but one problem I encountered on CentOS 7 was that with mod_php Apache was reading and writing files (e.g. in Moodledata) as user apache but on switching to PHP-FPM files were accessed as user php-fpm. This resulted in file permission issues and access had to be changed accordingly, mainly changing file ownership.
General help
[3.9.1]Switch to PHP FPM
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