As programme director for an London University engineering department, I've gently promoted DITA for the last five years or so. Although the department (alone in the university) also uses Moodle, it's taken me a while to see how interesting this discussion could become. From experience, though, I'd like to sound a note of caution.
What Matteo Scaramuccia suggests is very close to where we are now. I publish student information from a university CCMS to my desktop and re-route the result to Moodle, and this human intervention can surely be worked round. A significant issue is that most of our teaching content is mathematical, full maths support comes only with the DITA 1.3, DITA 1.3 is still just around the corner and our CCMS provider is a little slow to catch up. Meanwhile, most DITA teaching materials are written and published through Oxygen XML Editor, which provides a rich variety of output formats.
Where teaching is primarily face-to-face SCORM is a less useful format than WebHelp with Feedback, which promotes genuine student feedback (especially as we allow questions to be posed anonymously). A recent presentation by Hal Trent pointed towards an interesting fusion of these formats, showing just how wide the range of possible outputs could be once your content is cast in modular, structured form.
Matteo says that "AFAIK Moodle will never be able to read maps and create an output from there". Why not? If a lightweight CCMS (Drupal?) could be integrated, content could be uploaded in topic/map form and Moodle could use DITA-OT to construct whatever activities and resources you asked for. One of the core benefits of DITA is the ability to repurpose content from a common pool. Much of the fundamental content in programmes like ours is common between faculties and universities, and changes little with time. The freedom to render in any format could save a lot of the effort wasted by academics converting a predecessor's course materials from one favourite page format (LaTeX? Word?) to another.
However, the technical communications world where DITA flourishes is one in which writers are used to working systematically in teams. Academics just aren't like that. A few of my colleagues are as excited as I am by DITA's possibilities. For the rest DITA might be an easy sell if writing it was easy. It's not that difficult, but in a world where Microsoft Office is still the benchmark and even the use of styles is unusual, asking authors to submit to a Document Type Description isn't going to be easy.
Pat Leevers