Hi Richard,
typically software applications must be installed on the machine that the user is using. - you could theoretically provide the install files inside moodle for people to
download and install. - however you would have to give them licence keys etc. - this is likely to break any licencing agreement you have with Autograph.
I notice that Autograph uses Internet Explorer to use the content. - Autograph may have a web server install version of their software available - I suggest you try posting in the Autograph forums here:
http://www.autograph-maths.com/cgi-bin/yabb/YaBB.cgi
If you can install a web based version of autograph, you will be able to link to this from inside your moodle course.
good luck!
Dan