This may be a little over the top considering your original thread, Kathryn, but it may offer some insight as well, or at least a different perspective. Essentially, there are a raft of other considerations as well. Each of them revolve around the basic ideas of who owns the Moodle, who is using the Moodle and where does everyone else fit into it? If you have a bog standard Moodle, then as Moodle 2.1 is released, you are going to have a fairly powerful LMS that will provide you with everything you need. It can also be expected that you are going to have a number of years of trouble free motoring, apart from regular servicing and maintainance. People moving away from Standard releases tend to have more trouble as they seem to introduce inconsistencies in their efforts to make Moodle "better".
IM(NS)HO, Moodle is all about the people who are using it, and admins often forget that. It is really the end User that is important, and does Moodle deliver what they need, not what I want to give them, but what they need. Considering Moodle from that perpective, a lot of things become that much simpler, that much clearer. Sure, Moodle has shortcomings, but it provides what Users need.
Will Moodle meet my all organisational requirements? Not at all likely, but generic tools like Moodle can be tailored, considerably more easily than proprietal software, and this is where the problems come into it. The further you move away from a bog standard Moodle, the more likely a major issue will arise. Unless you take a Moodle and are prepared to rebuild it the way that meets your every need and never introduce any code you do not produce yourself, you are just asking for trouble. If you do not have the time to do it, then keep it as standard as you can and an eye out for specific improvements and updates that better suit your requirements. Better still, use the Moodle Tracker to request specific improvements and updates.
As a general observation, ever looked at a mechanic's toolbox? They know that no single tool will ever meet all needs, hence the huge number of tools. Software is usually off the shelf, generic tools, and are never going to meet every need or expectation. It is how you react to that inability that counts here. You can get all huffy like some and whine a lot but contribute nothing, you could do something else with another product, or you can build your own, or you can, if the opportunity arises as it does here, work with a group of people, a community, to try and make gradual improvements to the generic tool. Whatever you would like to do, that is your real option with Moodle, but not so with proprietal tools.
So what you you want, what do your Users need. Resolve that and things will become a lot simpler.