I've been asked this question many times when I get in touch with universities and propose solutions with Moodle Alfresco and the sort.
I would advice you to pick a solid partner and sign an SLA (Service Level Agreement) with them.
Such contracts contain clauses that depending on response times and server up times express levels of vendor liability.
A good first step would be to the partners network to find vendors.
Hope it helps,
Matías
Lounge
Moodle as a commercial alternative
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