If we go with Vue
To clarify, this is not about choosing a new JS infrastructure in Moodle at all. It was never intended to be like that.
The whole point of meetings and discussions like this is sharing experience and show what various community developers do in their plugins and customisations. I happen to know that Guy and some others have tried integrating Vue.js with Moodle and it does not hurt to see what can be achieved with these alternative approaches, what worked smoothly and what did not.
As far as I know, there is no near future plan to pick yet another JS framework for Moodle core. Quite opposite really - the core tends to aim to rely on standard ES6 modules only without additional dependency layers.
That does not mean we should isolate ourselves from innovation, experimentation and research.
hope it isn't like how YUI was chosen over JQuery back in the day
YUI was integrated into Moodle on 13 July 2006, one month and 13 days before the jQuery's initial release. Technically jQuery did not exist yet. Let us once and for all stop playing this Monday morning quarterback discussions.