This part:
"I filled only activity name, tool URL, consumer key, and secret.(This is like LTI 1.1.)"
please provide specifics ... to all of them ... the actual entries you made.
Tuner output ... one that catches my eye:
[!!] Aborted connections: 9.73% (11/113)
Indicates there might be some issues in connectivity between the Moodle code on the web server and the DB server. Apache error logs might also show that.
and this one:
Reduce or eliminate unclosed connections and network issues
Is the DB server on the same server as the moodle code it should be using socket connections.
'spirit of sharing', Ken