What sort of "integration" are you thinking of? If you share some details of what features you'd imagine an integrated Moodle/SfB deployment to have, someone can probably point you to the correct plugin type on the Moodle side.
In any case, you'll want to start by looking at what API SfB offers for integrating with other systems. If it doesn't have the ability to send and receive the data you're thinking of programmatically, I'm afraid you might be at a dead end.
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Moodle Integration With Skype for Business
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