Not available in standard Moodle, but Penny Leach has been working on a Matrix question type that does exactly what you want. It is work in progress, which you can see here: http://cvs.moodle.org/contrib/plugins/question/type/matrix/?pathrev=MOODLE_19_STABLE.
I think it is at a state where it is usable, and testing would be appreciated.
Quiz
Unknown question type - grid??
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